Richard M Weinshilboum Selected Research

Leukopenia

1/2022	Identification of Two Genetic Loci Associated with Leukopenia after Chemotherapy in Patients with Breast Cancer.
1/2015	Myelotoxicity after high-dose methotrexate in childhood acute leukemia is influenced by 6-mercaptopurine dosing but not by intermediate thiopurine methyltransferase activity.

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Richard M Weinshilboum Research Topics

Disease

53	Breast Neoplasms (Breast Cancer) 01/2023 - 08/2003
25	Neoplasms (Cancer) 01/2023 - 03/2006
14	Major Depressive Disorder (Major Depressive Disorders) 11/2022 - 03/2013
6	Inflammation (Inflammations) 01/2022 - 01/2017
5	Prostatic Neoplasms (Prostate Cancer) 01/2023 - 01/2018
3	Alcoholism (Alcohol Abuse) 11/2023 - 01/2022
3	Bipolar Disorder (Manic Depressive Psychosis) 12/2021 - 12/2020
3	T-Cell Leukemia (Leukemia, T Cell) 01/2018 - 03/2012
3	Drug-Related Side Effects and Adverse Reactions 01/2017 - 03/2004
3	Carcinogenesis 12/2007 - 03/2002
2	Heart Failure 10/2023 - 01/2022
2	Osteoporosis 11/2022 - 10/2014
2	Triple Negative Breast Neoplasms 06/2022 - 01/2018
2	Leukopenia 01/2022 - 01/2015
2	Obesity 01/2022 - 01/2019
2	Ulcerative Colitis 10/2020 - 07/2002
2	Neutropenia 01/2018 - 01/2015
2	Musculoskeletal Pain 03/2016 - 03/2012
2	Hypertension (High Blood Pressure) 02/2015 - 01/2014
2	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2015 - 12/2010
2	Colorectal Neoplasms (Colorectal Cancer) 01/2013 - 07/2007
2	Lung Neoplasms (Lung Cancer) 03/2010 - 04/2006
1	Substance-Related Disorders (Drug Abuse) 11/2023
1	Fibrosis (Cirrhosis) 10/2023
1	Mood Disorders (Mood Disorder) 11/2022
1	Fatigue 11/2022
1	COVID-19 11/2022
1	Immune System Diseases (Immune Disorders) 11/2022
1	Opioid-Related Disorders (Opiate Addiction) 10/2022

Drug/Important Bio-Agent (IBA)

18	Aromatase InhibitorsIBA 10/2021 - 12/2005
16	Estrogens (Estrogen)FDA Link 01/2022 - 03/2002
11	Biomarkers (Surrogate Marker)IBA 10/2023 - 07/2017
11	Anastrozole (Arimidex)FDA LinkGeneric 01/2022 - 01/2010
10	Estrogen ReceptorsIBA 01/2023 - 01/2013
10	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 01/2021 - 01/2005
10	Tamoxifen FDA LinkGeneric 01/2021 - 01/2005
10	DNA (Deoxyribonucleic Acid)IBA 01/2017 - 07/2002
7	Cytochrome P-450 CYP2D6 (CYP2D6)IBA 01/2013 - 01/2005
6	Aromatase (CYP19)IBA 01/2020 - 12/2005
6	EnzymesIBA 11/2011 - 01/2005
5	exemestane (Aromasin)FDA Link 01/2022 - 12/2016
5	Estradiol (Delestrogen)FDA LinkGeneric 01/2020 - 01/2010
5	Selective Estrogen Receptor Modulators (SERM)IBA 08/2017 - 11/2011
4	Hormones (Hormone)IBA 10/2021 - 08/2003
3	Abiraterone AcetateIBA 01/2023 - 01/2018
3	abirateroneIBA 12/2022 - 01/2018
3	GlucocorticoidsIBA 11/2022 - 12/2021
3	CytokinesIBA 01/2022 - 03/2012
3	Long Noncoding RNAIBA 12/2021 - 12/2016
3	Metformin (Glucophage)FDA LinkGeneric 01/2021 - 01/2015
3	Antidepressive Agents (Antidepressants)IBA 01/2021 - 01/2005
3	Estrone FDA Link 01/2020 - 01/2010
3	Citalopram FDA LinkGeneric 01/2019 - 08/2014
3	Escitalopram FDA Link 01/2019 - 08/2014
3	Bevacizumab (Avastin)FDA Link 01/2018 - 12/2015
3	Gemcitabine FDA Link 06/2010 - 03/2006
2	Androgen Receptors (Androgen Receptor)IBA 01/2023 - 06/2022
2	Prednisone (Sone)FDA LinkGeneric 12/2022 - 01/2018
2	Oxycodone (Oxycontin)FDA LinkGeneric 10/2022 - 08/2014
2	Trastuzumab (Herceptin)FDA Link 01/2022 - 01/2022
2	Poly(ADP-ribose) Polymerase InhibitorsIBA 01/2022 - 08/2017
2	Methotrexate (Mexate)FDA LinkGeneric 01/2022 - 01/2015
2	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2022
2	Acamprosate (Campral)FDA Link 01/2022 - 01/2022
2	Letrozole (Femara)FDA LinkGeneric 01/2022 - 01/2020
2	RNA (Ribonucleic Acid)IBA 01/2022 - 12/2014
2	AnthracyclinesIBA 01/2022 - 01/2018
2	CholesterolIBA 01/2022 - 02/2015
2	Anticonvulsants (Antiepileptic Drugs)IBA 01/2021 - 12/2020
2	afimoxifene (hydroxytamoxifen)IBA 06/2019 - 10/2009
2	Hypoglycemic Agents (Hypoglycemics)IBA 01/2018 - 01/2015
2	Cytochrome P-450 CYP3AIBA 01/2018 - 01/2005
2	P-2 (P 2)IBA 01/2017 - 07/2013
2	Mercaptopurine (6 Mercaptopurine)FDA LinkGeneric 01/2015 - 12/2010
2	Raloxifene Hydrochloride (Evista)FDA Link 07/2013 - 11/2011
2	pyrimidineIBA 11/2011 - 07/2007
2	purineIBA 11/2011 - 07/2007
2	Cytochrome P-450 CYP2D6 InhibitorsIBA 11/2011 - 01/2005
2	Acetaminophen (Paracetamol)FDA LinkGeneric 03/2011 - 03/2008
2	2-mercaptopurineIBA 12/2010 - 03/2004
2	CytidineIBA 06/2010 - 11/2009
2	4-hydroxy-N-desmethyltamoxifenIBA 06/2010 - 10/2009
2	Glutathione (Reduced Glutathione)IBA 03/2010 - 04/2006
2	PlatinumIBA 03/2010 - 04/2006
2	Antineoplastic Agents (Antineoplastics)IBA 06/2008 - 12/2007
1	fibroblast growth factor 21IBA 11/2023
1	Chromogranin AIBA 01/2023
1	enzalutamideIBA 01/2023
1	RAD140IBA 01/2023
1	Therapeutic UsesIBA 01/2023
1	ChromatinIBA 01/2023
1	Duloxetine Hydrochloride (Cymbalta)FDA Link 11/2022
1	Antiviral Agents (Antivirals)IBA 11/2022
1	Fluoxetine (Prozac)FDA LinkGeneric 11/2022
1	Opioid Analgesics (Opioids)IBA 10/2022

Therapy/Procedure

31	Therapeutics 11/2023 - 01/2005
18	Drug Therapy (Chemotherapy) 10/2023 - 07/2007
5	Neoadjuvant Therapy 06/2022 - 01/2010
4	Castration 01/2023 - 01/2018
2	Chemoprevention 01/2017 - 11/2011